A New Phase for Structural Biology - with Carol Robinson
Δημοσιεύτηκε στις 6 Ιουλ 2016
Carol
Robinson’s eccentric research transformed the field of structural
biology by studying proteins in the vapour phase, rather than as
solutions or solids. Her approach proved to be unpredictably worthwhile
and is providing a new view of protein interactions.
Sorry for the sound towards the end of the video – we had a technical mishap unfortunately :(
Subscribe for regular science videos: http://bit.ly/RiSubscRibe
Knowing
the shape of proteins is crucial for our understanding of human health
and for developing new drugs. To do this current methods require
proteins to be dissolved in a solution or locked in a crystal lattice.
These approaches are incredibly powerful and are the mainstay of the
field of structural biology as we know it. But what about the third
phase? How would proteins survive once they have gone beyond solid and
solution phases and released into the atmosphere?
While many
scientists thought that proteins would no longer maintain their shape in
the vapour phase Carol Robinson embarked on eccentric research into
studying proteins freely moving within in this phase. This work proved
to be unpredictably worthwhile, and her gas phase structural biology is
now providing a new view of dynamic interactions between proteins,
lipids and drugs.
Dame Carol Robinson is a British chemist,
working as a Royal Society Research Professor at the Physical and
Theoretical Chemistry Laboratory at the University of Oxford.
Carol
is the first female Professor of Chemistry at the University of Oxford
and was previously the first female Professor of Chemistry at the
University of Cambridge. She is renowned for pioneering the use of mass
spectrometry as an analytical tool and for her ground-breaking research
into the 3D structure of proteins.
Subscribe for regular science videos: http://bit.ly/RiSubscRibe
Watch more science videos on the Ri Channel http://richannel.org
The Ri is on Twitter: http://twitter.com/ri_science
and Facebook: http://www.facebook.com/royalinstitution
and Tumblr: http://ri-science.tumblr.com/
Subscribe for the latest science videos: http://richannel.org/newsletter Our editorial policy: http://richannel.org/home/editorial-p...
Robinson’s eccentric research transformed the field of structural
biology by studying proteins in the vapour phase, rather than as
solutions or solids. Her approach proved to be unpredictably worthwhile
and is providing a new view of protein interactions.
Sorry for the sound towards the end of the video – we had a technical mishap unfortunately :(
Subscribe for regular science videos: http://bit.ly/RiSubscRibe
Knowing
the shape of proteins is crucial for our understanding of human health
and for developing new drugs. To do this current methods require
proteins to be dissolved in a solution or locked in a crystal lattice.
These approaches are incredibly powerful and are the mainstay of the
field of structural biology as we know it. But what about the third
phase? How would proteins survive once they have gone beyond solid and
solution phases and released into the atmosphere?
While many
scientists thought that proteins would no longer maintain their shape in
the vapour phase Carol Robinson embarked on eccentric research into
studying proteins freely moving within in this phase. This work proved
to be unpredictably worthwhile, and her gas phase structural biology is
now providing a new view of dynamic interactions between proteins,
lipids and drugs.
Dame Carol Robinson is a British chemist,
working as a Royal Society Research Professor at the Physical and
Theoretical Chemistry Laboratory at the University of Oxford.
Carol
is the first female Professor of Chemistry at the University of Oxford
and was previously the first female Professor of Chemistry at the
University of Cambridge. She is renowned for pioneering the use of mass
spectrometry as an analytical tool and for her ground-breaking research
into the 3D structure of proteins.
Subscribe for regular science videos: http://bit.ly/RiSubscRibe
Watch more science videos on the Ri Channel http://richannel.org
The Ri is on Twitter: http://twitter.com/ri_science
and Facebook: http://www.facebook.com/royalinstitution
and Tumblr: http://ri-science.tumblr.com/
Subscribe for the latest science videos: http://richannel.org/newsletter Our editorial policy: http://richannel.org/home/editorial-p...
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ANAΡΤΗΣΗ ΑΠΟ ΤΟ YOUTUBE 17/7/2016
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